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Botulinum Toxin - 3 Vials x 150 IU
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| |  | | Package: 3 Vials x 150 IU
Usage: Injectable
Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating,etc.
Produced by: China
| | Price: $305.00 |  |
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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online
Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)
DESCRIPTION:
Botulinum Toxin Type A is kind-A toxin which encloses 150 IU in one vial and may be injected into one person. Botulinum Toxin Type A is a category of medication to correct light wrinkles as well as shrink the expression.
This injection is a disinfect, lyophilized formula of cleansed botulinum toxin type A, manufactured from the unfinished toxin of the culture of the Hall strain of Clostridium botulinum grown in a medium enclosing trypticase also yeast extract. A series of refining practice were used to make a transparent complex consisting of the active high molecular weight toxin protein as well as an connected hemagglutinin. Once re-diluted and dialyzed the crystalline toxin, a correct volume of the hygienic cleaned (0.2 microns) toxin were added to a solution containing gelatin-dextran-sucrose, and then lyophilized. Every vial of BTXA contains 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.
SUGGESTIONS:
This preparation is suggested for the cure of blepharospasm, hemi facial spasm in adults also some varienties of strabismus, particularly for acute paralytic strabismus, comitant strabismus, strabismus caused by endocrine myopathy and strabismus which cannot be rectified with operation. Anti-Wrinkle, Thin looks and legs.
USAGE AND DOSE:
1. Site for inoculation:
- For blepharospasm: the injection must be administrated intramuscularly at some points of superior and lower covers, i.e., using 4 to 5 places of inoculation into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial tremor: besides the places mentioned above, three other places on middle, lower face also cheek have to be inoculated intramuscularly. BTXA (Botulinum Toxin Type A for Therapy) can be inserted at the places of two sides of eyebrow, upper lip or the lower jaw according to the diseases.
- For strabismus: the BTXA (Botulinum Toxin Type A for Therapy) is injected using a coaxial electrode needle with electromyography supervision or amplifier under topical anesthesia of 0.5% Decarine. The inoculations into extra ocular muscles are selected according to the kind as well lacation of strabismus.
2. Measuring:
150 IU must be thinning into 2.0-2.5ml sterilized water before inserting.
Dilute with sterile normal saline agreeing to different requests before using. The white loose product turns to be colorless or yellowish transparent solution after the thinning.
- For blepharopasm and hemi facial tremor: the inoculation can be indicated following above advices. The initial measure of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. If the primary treatment is considered deficient one week later, an additional injection could be suggested. Dual dosing of 5 U / 0.1 ml can be suggested to recrudescent patients. But the limitation of entire measure of 55 U for 1 injection and 200 U for 1 month should not be exceeded.
- For strabismus: for vertical as well horizontal muscle strabismus of less than 20 prism diopters, the primary dosing into each muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the initial dosing into each muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the first dose into every muscle is 2.5 U also may be increase (to 5.0 every) depending on the response; for insistent VI cranial nerve paralysis lasted for more than 1 month. The inserting volume into each muscle must not exceed 0.1 ml. To people, having insufficient reply, supplementary inoculation can be suggested. To recrudescent patients, the dosage can be repeated or improved irregularly. But for every muscle the maximum dosing should be less than 5 U / inj.
The Dilution of BTXA:
The thinning of BTXA (Botulinum Toxin Type A for Therapy) with sterilized normal saline should be prepared sensibly on the basis of real request. Succeding is a reference table of watering to be suggested. The vial should be shaking gently after adding sterile normal saline to the whole dissolving. The reconstituted BTXA (Botulinum Toxin Type A for Therapy) must be injected at once or stored in refrigerator at 2-8 degrees as well to be used within 4 hours. The ampoule as well as the syringe used with BTXA (Botulinum Toxin Type A for Therapy) also the lasting BTXA solution has to be disposed after sterilization.
UNDESIRABLE FEEDBACKS:
Short-term ptosis of the eyelid, downside of the lower eyelid, reduced blinking, eyelid close partly, weakness of face muscles, etc. can appear to a few patients who inject this medication therapy for blepharospasm as well hemi facial shudder. But, all the signs will vanish without any therapy within 3 to 8 weeks. Temporary and diverse point of ptosis of the eyelid, vertical deviancy also infrequently mydriasis, which connected to the circulation of the toxin to the muscles adjacent, may occur to some patients who inject BTXA (Botulinum Toxin Type A for Therapy) cure for strabismus. The signs will vanish without any remedy within a few weeks.
CONTRAINDICATIONS:
This product is not indicated in people with anaphylactic structure as well recognized allergic reaction to this medication.
NOTICES:
The inoculation way has to be indicated later to people who have infection, grave infectious diseases also carefully to the persons with heart, liver, lung troubles, active tuberculosis, blood problems also pregnant women.
Botulinum toxin could be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of drugs must not be used during the using of BTXA.
BTXA is in low effect or without any result to the patients in the next situations: strabismus above 50 prism diopters, fixed strabismus, strabismus caused by excessively serious operation, chronic paralysis strabismus, as well as chronic VI or III cranial nerve paralysis, serious muscle fiber contracture.
1:1000 adrenalines must be set in case of occasional accident.
SHELF LIFE:
3 years from the day of lyophilization. The action is clear and may be last six months.
KEEPING:
Store at a temperature of -5 to -20 gr C (23 to -4 gr F). Keep unused vial at -5 temperatures.
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