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Botulinum Toxin - 1 Vial x 150 IU
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| |  | | Package: 1 Vial x 150 IU
Usage: Injectable
Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating,etc.
Produced by: China
| | Price: $145.00 |  |
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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online
Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)
DESCRIPTION:
Botulinum Toxin Type A is category-A toxin which has 150 IU in one vial and can be injected into one person. Botulinum Toxin Type A is a kind of preparation to correct small wrinkles as well as shrink the look.
This medication is a sterilized, lyophilized form of cleansed botulinum toxin type A, created from the unfinished toxin of the culture of the Hall strain of Clostridium botulinum developed in a medium holding trypticase and yeast extract. A sequence of refining method were extracted to make a limpid complex consisting of the active high molecular weight toxin protein and an allied hemagglutinin. Next re-diluted and dialyzed the crystalline toxin, a correct amount of the hygienic clarified (0.2 microns) toxin were added to a solution having gelatin-dextran-sucrose, and then lyophilized. Each vial of BTXA contains 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.
INDICATIONS:
This preparation is suggested for the handling of blepharospasm, hemi facial tremor in adults and some forms of strabismus, specialy for important paralytic strabismus, comitant strabismus, strabismus caused by endocrine myopathy and strabismus which cannot be modified through surgery. Anti-Wrinkle, Thin faces as well legs.
USAGE AND DOSAGE:
1. Place for insertion:
- For blepharospasm: the inoculation has to be used intramuscularly at some locations of upper also lower lids, i.e., using 4 to 5 places of injection into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial tremor: besides the locations mentioned above, three other points on middle, lower face also cheek must be given intramuscularly. BTXA may be inoculated at the locations of two sides of eyebrow, upper lip or the lower jaw agreeing to the sicknesses.
- For strabismus: the BTXA is injected using a coaxial electrode needle with electromyography control or amplifier under topical anesthesia of 0.5% Decarine. The insertions into additional ocular muscles are selected according to the type and lacation of strabismus.
2. Measuring:
150 IU have to be thinning into 2.0-2.5ml sterilized water before inoculating.
Dissolve with sterile normal saline agreeing to different necessities before injecting. The white loose product changes to be monochrome or yellowish clear solution after the melting.
- For blepharopasm also hemi facial spasm: the insertion may be given following above instructions. The first dosing of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. In case the primary handling is considered inadequate one week later, an additional insertion can be given. Dual dosage of 5 U / 0.1 ml may be suggested to recrudescent people. But the restriction of entire dosage of 55 U for 1 injection and 200 U for 1 month must not be exceeded.
- For strabismus: for vertical as well horizontal muscle strabismus of less than 20 prism diopters, the first dose into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the initial dosing into each muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the first dose into every muscle is 2.5 U also could be rised (to 5.0 every) depending on the response; for persistent VI cranial nerve paralysis lasted for more than 1 month. The inserting volume into ever muscle must not more 0.1 ml. To persons, having insufficient response, supplementary insertion can be suggested. To recrudescent people, the dosage can be repeated or amplified irregularly. But for every muscle the supreme measure has to be less than 5 U / inj.
The Watering of BTXA (Botulinum Toxin Type A for Therapy):
The dissolving of BTXA (Botulinum Toxin Type A for Therapy) with sterilized normal saline should be done carefully on the basis of real request. Following is a reference table of thinning to be recommended. The vial has to be trembling lightly after adding sterile normal saline to the complete thinning. The dilution BTXA has to be injected at once or kept in refrigerator at 2 to 8 degrees and to be injected within 4 hours. The ampoule also the syringe used with this injection also the lasting BTXA solution should be prepared after sterilization.
NEGATIVE RESULTS:
Temporary ptosis of the eyelid, negative of the minor eyelid, minimized blinking, eyelid close in part, dimless of face muscles, etc. can occur to a few individuals who inject this medication therapy for blepharospasm also hemi facial shudder. But, all the symptoms will disappear without any treatment within 3 to eight weeks. Temporary also different degree of ptosis of the eyelid, vertical deviation and seldom mydriasis, which associated to the transmission of the toxin to the muscles adjacent, can arise to some patients who inject this medication remedy for strabismus. The symptoms will disappear without any therapy within a few weeks.
CONTRAINDICATIONS:
This preparation is not recommended in patients with anaphylactic parts as well recognized allergic reaction to this preparation.
ADVICES:
The injection procedure must be indicated later to persons who have fever, acute infectious diseases also prudently to the patients with heart, liver, lung troubles, active tuberculosis, blood malady also pregnant women.
Botulinum toxin can be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of medicines must not be taken during the inserting of BTXA.
BTXA (Botulinum Toxin Type A for Therapy) is in low reaction or without any result to the patients in the following situations: strabismus above 50 prism diopters, fixed strabismus, strabismus caused by excessively corrected operation, chronic paralysis strabismus, also chronic VI or III cranial nerve paralysis, serious muscle fiber contracture.
1:1000 adrenalines should be set in case of occasional accident.
SHELF LIFE:
Three years from the day of lyophilization. The action is obvious and may be last six months.
STORING:
Store at a temperature of -5 to -20 gr C (23 to -4 gr F). Keep unopened vial at -5 temperatures.
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